Smythies JR. Analysis of Perception. London, Routledge & Kegan Paul in the International Library of Psychology, Philosophy and Scientific Method, 1956.
Smythies JR. Schizophrenia: Chemistry, Metabolism and Treatment. Springfield, Illinois, Charles C. Thomas, 1963.
Smythies JR. Brain and Mind. London, Routledge & Kegan Paul, editor and contributor of essay "The representative theory of perception", 1965.
Smythies JR. The Neurological Foundations of Psychiatry. Oxford, Blackwell. 1966
Smythies JR. (with HE Himwich and SS Kety, editors) Amines and Schizophrenia. New York, Pergamon Press. 1966
Smythies J. Science and ESP. London, Routledge & Kegan Paul, 1967
Smythies JR. Biological Psychiatry. Heinemann, 1968. German edition, 1971.
Smythies JR. (with Arthur Koestler, editors). Beyond Reductionism. London, Macmillan, 1969.
Smythies JR. Brain Mechanisms and Behaviour. Oxford, Blackwell, 1970. Japanese edition, 1973.
Smythies JR. and Corbett LC. Psychiatry for Students of Medicine. London, Heinemann, 1976. Spanish edition, 1981.
Smythies JR and Bradley RJ (editors). Receptors in Pharmacology. New York, Dekker, 1978.
Smythies J. The Walls of Plato’s Cave. Aldershot, Avebury Press, 1994.
Smythies J. Every Person’s Guide to Antioxidants. Rutgers University Press, 1998.
Smythies JR. The Dynamic Neuron. Cambridge MA., MIT Press, 2002.
Smythies J. Poems from the Edge of Time. Pulborough, Ellis, 2002.
Smythies J. (Editor) Schizophrenia. A disorder of synaptic plasticity. Special volume (59) in The International Review of Neurobiology, San Diego, Elsevier, 2004.
Smythies J. The Neuromodulators. International Review of Neurobiology, San Diego, Elsevier, 2005.
Smythies J. Bitter Fruit. Amazon.com (Booksurge) 2006.
Smythies J. & Smythies V. Two Coins in the Fountain. (Joint autobiography). Amazon.com (Booksurge) 2006.
Smythies J. The Trial of God. (Satirical play) Amazon.com (Booksurge) 2006.
Smythies J. Planet in Peril. Pulborough, Ellis, 2007